Anencephaly and spina bifida (ASB) and retroversion.
نویسنده
چکیده
Despite the wealth of epidemiological material of the last decade, birth defects are still the chief cause of perinatal mortality and no significant breakthrough in understanding or reduction has yet been seen. Many proposed aetiological factors are still being evaluated. This report suggests a possible, simple, remediable factor in the aetiology of defects of the central nervous system.
منابع مشابه
Sexes of affected cases in sibships containing two or more members with anencephaly or spina bifida.
A study has been made of the sexes of the affected within sibships containing two or more members with anencephaly or spina bifida (ASB). There is no clear evidence for variation between ASB-prone women in their propensity to bear affected cases of one sex rather than the other. It is suggested that the point should be regarded as open until further data have settled the issue.
متن کاملBirth ranks of spontaneous abortions in sibships of children affected by anencephaly or spina bifida.
Data on the birth ranks of miscarriages within sibships in which a case of anencephaly or spina bifida (ASB) had occurred were analysed by the Haldane-Smith statistical test. This showed that miscarriages in ASB sibships tend to have a negative birth order effect--that is, they occur in earlier rather than later pregnancies within the sibship. The strongest source of bias in this analysis--the ...
متن کاملPotato avoidance during pregnancy in women with a previous infant with either anencephaly and/or spina bifida.
This investigation is a direct attempt to test Renwick's (1972) hypothesis that 95% of anencephaly and spina bifida (ASB) is preventable by the avoidance of potatoes during pregnancy. Although the numbers involved in the study are small, the investigation fails to support the concept that short-term avoidance of potatoes before conception and throughout pregnancy in women who have had a previou...
متن کاملShifting genetic patterns in anencephaly and spina bifida.
The long-term decline in the incidence of the neural tube malformations, anencephaly and spina bifida (ASB), ended in the mid-1950's in New York State. Since that time, the rate of these birth defects has remained between 1 and 1.5/1000 births. In this low incidence population, we tested the basic tenets which support a genetic aetiology. We found that the full sib recurrence rate (1.8%) was hi...
متن کاملNeural-tube defects: importance of a history of abortion in aetiology.
The overall incidence of anencephaly and spina bifida (ASB) in 69,056 pregnancies was 4.7/1000 births. ASB was more common (8.4/1000 births) among children of mothers who had had two or more abortions, but the increased risk was confined to spina bifida. A history of abortion was more common in older women and women of higher parity, but this was not matched by a similar increase in the inciden...
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ورودعنوان ژورنال:
- Journal of epidemiology and community health
دوره 33 4 شماره
صفحات -
تاریخ انتشار 1979